Sequential Testing

Below are listed sequential tests that may be required for appropriate results to be given, which may delay the release of the result of the initial test while they are being performed. These will be performed as and when required by the laboratory staff, and are listed here for reference only.

Unauthorised tests that are part of a set of requests made on a single form may also hold up the hard copy report of the results, but should not hold up electronic reporting.

Some tests may require sending to external laboratories due to issues with specific samples, or analyser downtime. For more information on any specific sendaway test, see the TransfusionTest Information section.

TRANSFUSION
INITIAL TEST	SUB-TEST	SEQUENTIAL TEST	PURPOSE
Group and Save	Group	DCT (IgG/Complement fractions)	To investigate haemolytic anaemia.
	Antibody Screen	Antibody panel (Panel 1)	To determine the identity of any non-ABO red cell antibodies present in the sample.
		Antibody panel (Panel 2)	As above, where the result of the first panel is ambiguous.
		Rh/K phenotype	To determine the absence of any of the C, E, c, e and K antigens on the patient's red cells, enabling blood to be issued that is less likely to provoke the formation of antibodies.
		Manual crossmatch	To determine if blood components are compatible for patients when electronic issue is not available.
Antenatal Group and Screen	Group	N/A
Antenatal Group and Screen	Antibody Screen	Antibody panel (Panel 2)	To determine the identity of any non-ABO red cell antibodies present in the sample.
Baby Group and Direct Coombs Test (DCT)	Baby Group	Du test	To detect whether weak RhD antigens are present on the red cell that may lead to the patient being incorrectly grouped as RhD negative.

Phlebotomy

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Sequential Testing