Transfusion Test Information

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Unless otherwise specified, sample type required is venous blood in EDTA anticoagulant.

Routine hospital turnaround times listed in each test refer to the average time taken from receipt in the laboratory to authorisation, while routine GP turnaround times refer to the average time between when they are collected by the transport and authorisation. They are not guaranteed maximum turnaround times, as delays in transport would lead to delays in analysis, and sequential tests may be required to provide appropriate results. A list of sequential tests is available in the Sequential Testing section.

 "Working day" refers to Monday to Friday 08:00-17:00 (not including Bank Holidays).

Additional requests

Transfusion samples are stored for 28 days during which additional work may be carried out, assuming there is sufficient remaining sample volume to work with and the sample remains valid (see the Group & Save/Crossmatch section for details).

For add-on tests to be performed, a request form must be sent to the laboratory indicating that the request is for add-on testing.

Note: Kleihauers are unsuitable for requesting as add-on tests to already-processed samples. Please discuss with laboratory if necessary.

Transfusion
Adult Group and Save
Antenatal Group and Screen
Paediatric/neonatal Group and Save (>4 months only)
Baby group and DCT (<4 months only)
Crossmatch (For adults and neonates >4 months old)
Issue of Blood Products: Blood for Babies (For neonates <4 months old)
Issue of Blood Products: Platelets
Issue of Blood Products: FFP, Octaplas, Cryoprecipitate
Issue of Blood Products: Granulocytes
Issue of Blood Products: Anti-D
Issue of Blood Products: Human Albumin Solution (HAS)
Issue of Blood Products: Coagulation Factor Proteins (Advate, F8Y, Wilate, Octaplex, Novoseven, Riastap)
Kleihauer
Direct Agglutination Test/Direct Coombs Test
Cold Agglutinins
Transfusion Reaction Investigation

Sendaway Tests

Important note: All sendaway tests are either requested exclusively by Haematology consultants or laboratory staff, or can be requested by other clinical staff only if a Haematology consultant has authorised the request.

All tests are performed by one of NHS Blood & Transplant's (NHSBT) Red Cell Immunohaematology (RCI) or Histocompatability & Immunogenetics (H&I) reference centres. The most common sendaway tests have their own dedicated test information pages linked below. The less common sendaway tests, and those sendaway tests that  this Transfusion laboratory already performs on-site, are listed below without linking to further details. Information can be provided by the Transfusion laboratory if requested.

All overdue sendaway requests are pursued routinely by laboratory staff. If there are any issues regarding pending results from a sendaway test, please contact this laboratory on extension 8451 or 8452 rather than the reference laboratory.

RCI:
Antibody investigation
ABO/Rh grouping problems investigation
Extended RBC phenotype
Crossmatch (Referral)
Antenatal alloantibody quantification
Autoimmune haemolytic anaemia/positive DAT
Haemolytic transfusion reaction investigation

H&I - Diagnostic laboratory:
Platelet Refractoriness due to HLA antibodies
Drug hypersensitivity/disease association
TRALI
Transfusion reaction investigation (TaGVHD and non-haemolytic)

H&I - Haemopoietic stem cell transplantation (HSCT):
HLA typing (for HSCT patients and donors)
Chimerism analysis
Blood grouping
HLA-specific antibody testing
Volunteer donor search

H&I - Platelet immunology:
Foetal/Neonatal Alloimmune Thrombocytopaenia (NAIT)
Platelet Refractoriness due to HPA antibodies
Autoimmune Thrombocytopaenia Investigation
Heparin Induced Thrombocytopaenia (HIT)
Other drug-induces antibody-mediated thrombocytopaenias
Post-transfusion purpura
Platelet membrane glycoprotein estimation
Vaccine Induced Thrombocytopenia

H&I - Granulocyte immunology:
Neonatal Autoimmune Neutropaenia (NAIN)
Adult autoimmune neutropaenia
Infant autoimmune neutropaenia
Drug induced antibody mediated neutropaenias