Assay

BCR-ABL1 Kinase domain mutations

Key Words

BCR-ABL1, Kinase, Domain, Mutation

Specimen Collection

Sample must be <72h old on receipt at reference laboratory. 20ml peripheral Blood EDTA.

Referral

This test is referred to another centre for analysis:

Laboratory for Molecular Haemato-Oncology (LMH)

King's College Hospital NHS Trust

Turnaround time

30 days from receipt at reference laboratory

Test indications

To test for resistance to therapy with first line Tyrosine kinase inhibitors (Eg Imatinib, Nilotinib, Dasatinib) 

Interferences

Contact referral laboratory for information

Reference Range

Contact referral laboratory for information

Minimum retesting interval

N/A