Assay

JAK2

Key Words

JAK2, Janus Kinase V617F

Specimen Collection

Mon-Thu only. If peripheral blood: 1x 7.5ml EDTA or 2x 3.4ml EDTA. If bone marrow: 1x 3.4ml EDTA.

Referral

This test is referred to another centre for analysis:
Haemato-Oncology Diagnostic Service

Level 3 Box 234
Addenbrookes Hospital
Hills Road
Cambridge
CB2 0QQ

Turnaround time

14 days from receipt at reference laboratory

Test indications

Suspected myeloproliferative neoplasm (Polycythaemia vera, essential thrombocythaemia, primary myelofibrosis)

Interferences

Contact referral laboratory for information. JAK2 negativity does not exclude myeloproliferative disease. Please discuss with Haematology if further testing is required (e.g. JAK2 exon 12, CALR, MPL).

Reference Range

Contact referral laboratory for information

Minimum retesting interval

JAK2 requests made within 90 days of a previous request on a patient are intervened.