Assay

Beta-2-glycoprotein-1 (IgG)

Key Words

Beta-2-glycoprotein-1 (B2GP)

Specimen Collection

Serum (Brown)

Turnaround time

7 Days

Test indications

Beta-2-GP-1 is a phospholipid binding protein and antibodies directed against this antigen are seen in patients suffering from the Anti-Phospholipid Syndrome (APS). This test is recommended in patients suspected of having APS in whom the lupus anticoagulant and anti-cardiolipin assays are negative, and can be helpful in other situations described in the 2012 BCSH guidelines (available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2012.09037.x/abstract).

Methodology

Enzyme immunoassay

Interferences

No known methodological interferences

Reference Range

Negative <7 U/mL

Equivocal 7-10 U/mL

Positive >10 U/mL

Analytical error

Contact laboratory x8454

Reference change value

N/A