Under conditions of normal renal function, creatinine is excreted by glomerular filtration. Creatinine determinations are performed for the diagnosis and monitoring of acute and chronic renal disease as well as for the monitoring of renal dialysis. Creatinine concentrations in urine can be used with serum creatinine to calculate a clearance rate known as a measure of glomerular filtration Rate (GFR).
Icterus (bilirubin) and some drugs may cause interference with the serum assay. Hydroxocobalamin may cause falsely low creatinine results in urine. To allow for an accurate GFR estimation the urine collection MUST be over a full 24 hour period
Contact lab for further details
See plasma creatinine and urine creatinine sections.
