Assay

Lupus Anticoagulant Screen

Key Words

Lupus anticoagulant, antiphospholipid syndrome, APS, DRVVT

Specimen Collection

3x 3.0ml Citrate (Green lid). Equivalent volume with 1.4ml Citrate for paediatric (Green lid) - Discuss with laboratory. Fill to mark. Samples will be processed up to 24 hours from the time of collection. Due to the nature of the assay, this test cannot easily be added on to routine coagulation requests sent with a single sample, UNLESS the assay is being performed on the day of receipt (which only occurs once per week). Contact the laboratory before requesting this test as an add-on.

Turnaround time

1 week

Test indications

Recurrent miscarriages, thrombosis in unusual sites, cerebrovascular accident, investigation of prolonged APTT as directed by the laboratory

Interferences

Lipaemia, haemolysis, anticoagulants

Reference Range

Adult: 0.80-1.24R. Reference ranges established in-house from local population.

Minimum retesting interval

Lupus Anticoagulant Screen requests made within 70 days of a previous request on a patient are intervened.