Assay

Gastric parietal cell antibodies (GPC)

Key Words

Pernicious Anaemia Associated abs , GPC

 Specimen Collection

Serum (brown)

Turnaround time

7 days

Test indications

These antibodies have a strong association with pernicious anaemia and autoimmune gastritis. Low titres are commonly found in normal elderly females.  Positive results will automatically be referred for Intrinsic factor antibodies which are more specific, but less sensitive, for pernicious anaemia. GPC antibodies can also be found in patients with autoimmune thyroid disease and Sjogren's syndrome.

Methodology

Indirect immunofluorescence

Interferences

No known methodological interferences

Reference Range

N/A

Analytical error

N/A

Reference change value

N/A